{"id":2998,"date":"2026-01-20T14:42:21","date_gmt":"2026-01-20T05:42:21","guid":{"rendered":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/?p=2998"},"modified":"2026-01-20T14:42:21","modified_gmt":"2026-01-20T05:42:21","slug":"kurri-kr-148","status":"publish","type":"post","link":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/kurri-kr-148\/","title":{"rendered":"KURRI-KR-148"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(I)\uff08\u5e73\u621020\u5e74\u5ea6\uff09
Proceedings of the Specialist Research Meeting on “Abnormal Protein Aggregation and the Folding Diseases, and Their Protection and Repair System”<\/p>\n\n\n\n

\u958b\u50ac\u65e5\uff1a2008\u5e7410\u67082\u65e5 (Octover 2, 2008)
\u7de8\u96c6\uff1a\u5b9a\u91d1 \u8c4a\u3001\u85e4\u4e95\u7d00\u5b50
Edited by\uff1aYutaka Sadakane and Noriko Fujii<\/p>\n\n\n\n

\u76ee\u6b21<\/strong><\/p>\n\n\n\n

    \n
  1. Asp\u6b8b\u57fa\u304a\u3088\u3073Asn\u6b8b\u57fa\u306e\u69cb\u9020\u5909\u5316\u5206\u6790\u6cd5\u306e\u958b\u767a\u3068\u30b3\u30f3\u30d5\u30a9\u30e1\u30fc\u30b7\u30e7\u30f3\u75c5\u3078\u306e\u5fdc\u7528 \/ \u5b9a\u91d1 \u8c4a\u3001\u6728\u8449\u656c\u5b50\u3001\u5ddd\u539f\u6b63\u535a\uff08\u4e5d\u5dde\u4fdd\u5065\u798f\u7949\u5927\u5b66\u30fb\u85ac\u5b66\u90e8\uff09 p.1<\/li>\n\n\n\n
  2. \u86cb\u767d\u8cea\u306e\u7570\u5e38\u6c88\u7740\u304c\u5f15\u304d\u8d77\u3053\u3059\u773c\u75be\u60a3 \/ \u52a0\u6cbb\u512a\u4e001<\/sup>\u3001\u85e4\u4e95\u7d00\u5b502<\/sup>\uff08\u7b51\u6ce2\u5927\u81e8\u5e8a\u533b\u5b66\u7cfb\u773c\u79d11<\/sup>\u3001\u4eac\u5927\u30fb\u539f\u5b50\u70892<\/sup>\uff09p.6<\/li>\n\n\n\n
  3. \u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30da\u30d7\u30c1\u30c9\u306e\u51dd\u96c6\u306b\u53ca\u307c\u3059D-\u30a2\u30b9\u30d1\u30e9\u30ae\u30f3\u9178\u306e\u5f71\u97ff \/ \u52a0\u85e4\u304f\u307f\u5b50\u3001\u696f\u3000\u76f4\u5b50\uff08\u6b66\u8535\u91ce\u5927\u30fb\u85ac\uff09 p.12<\/li>\n\n\n\n
  4. \u6c34\u6676\u4f53\u4e2d\u306e\u30af\u30ea\u30b9\u30bf\u30ea\u30f3\u306e\u51dd\u96c6\u30e1\u30ab\u30cb\u30ba\u30e0 \/ \u4e2d\u6fa4\u3000\u6d0b\u4ecb1<\/sup>\u3001\u7af9\u9f3b\u3000\u771e2*<\/sup>\u3001\u4f50\u91ce\u3000\u6d0b1<\/sup>\uff08\u6442\u5357\u5927\u5b66\u85ac\u5b66\u90e8\u85ac\u54c1\u7269\u6027\u5316\u5b66\u7814\u7a76\u5ba41<\/sup>\u3001\u6176\u61c9\u5927\u5b66\u85ac\u5b66\u90e8\u5206\u5b50\u6a5f\u80fd\u751f\u7406\u5b66\u8b1b\u5ea72<\/sup>\uff09 p.16<\/li>\n\n\n\n
  5. Age-related deamidations that lead to aggregation of crystallins in the lens \/ Kirsten. J. Lampi\uff08Oregon Health & Science University\uff09 p.21<\/li>\n\n\n\n
  6. \u86cb\u767d\u8cea\u306e\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u3068\u30a2\u30df\u30ed\u30a4\u30c9\u7dda\u7dad\u5f62\u6210 \/ \u5f8c\u85e4\u7950\u5150\uff08\u5927\u962a\u5927\u5b66\u30fb\u86cb\u767d\u8cea\u7814\u7a76\u6240\uff09 p.26<\/li>\n\n\n\n
  7. \u7570\u5e38\u51dd\u96c6\u306e\u30c8\u30ea\u30ac\u30fc\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u4e09\u6b21\u304a\u3088\u3073\u9ad8\u6b21\u69cb\u9020\u5909\u5316\u306e\u89e3\u660e\u306b\u5411\u3051\u3066 \/ \u68ee\u672c\u5e78\u751f\uff08\u4eac\u90fd\u5927\u5b66\u539f\u5b50\u7089\u5b9f\u9a13\u6240\uff09p.32<\/li>\n\n\n\n
  8. \u4e2d\u6027\u5b50\u5c0f\u89d2\u6563\u4e71\u6cd5\u306b\u3088\u308b\u7570\u5e38\u51dd\u96c6\u904e\u7a0b\u306e\u305d\u306e\u5834\u89b3\u6e2c \/ \u6749\u5c71\u6b63\u660e\u3001\u85e4\u4e95\u7d00\u5b50\u3001\u68ee\u672c\u5e78\u751f\u3001\u798f\u6c38\u4fca\u6674\uff08\u4eac\u90fd\u5927\u5b66\u539f\u5b50\u7089\u5b9f\u9a13\u6240 \uff09p.37<\/li>\n\n\n\n
  9. \u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u75c5\u3068D-\u30a2\u30df\u30ce\u9178\u542b\u6709\u30bf\u30f3\u30d1\u30af\u8cea\u4ee3\u8b1d\u6a5f\u69cb \/ \u6728\u91ce\u5185\u5fe0\u7a14\u3001\u85e4\u4e95\u7d00\u5b50\uff08\u4eac\u90fd\u5927\u5b66\u539f\u5b50\u7089\u5b9f\u9a13\u6240\uff09p.40<\/li>\n\n\n\n
  10. \u653e\u5c04\u7dda\u7d30\u80de\u304c\u3093\u5316\u306e\u7b2c\u4e00\u6a19\u7684\u306fDNA\u3067\u306a\u304f\u30bf\u30f3\u30d1\u30af\u640d\u50b7\u3067\u3042\u308b \/ \u6e21\u9089\u6b63\u5df1\uff08\u4eac\u90fd\u5927\u5b66\u539f\u5b50\u7089\u5b9f\u9a13\u6240\u653e\u5c04\u7dda\u751f\u547d\u79d1\u5b66\u7814\u7a76\u90e8\u9580\uff09p.44<\/li>\n<\/ol>\n\n\n\n

    Contents<\/strong><\/p>\n\n\n\n

      \n
    1. Analysis of structural alternations of L-Asp and L-Asn residues in peptides related to neuronal conformational disease \/ Yutaka Sadakane , Keiko Konoha, Masahiro Kawahara (School of Pharmaceutical Science, Kyushu University of Health and Welfare) p.1<\/li>\n\n\n\n
    2. Ocular diseases related to abnormal accumulation of modified proteins \/ Yuichi Kaji1<\/sup>\uff0c Noriko Fujii2<\/sup> (1<\/sup>Department of Ophthalmology, University of Tsukuba, 2<\/sup>RRI, Kyoto Univ.) p.6<\/li>\n\n\n\n
    3. Effect of D-aspartic acid on the amyloidal \u03b2 aggregation \/ K. Sakai-Kato* and N. Utsunomiya-Tate (Research Institute of Pharmaceutical Sciences, Musashino University (*present affiliation: National Institute of Health Sciences)) p.12<\/li>\n\n\n\n
    4. The Aggregation Mechanism of Lens Crystallins \/ Yosuke Nakazawa1<\/sup>, Makoto Takehana2*<\/sup> and Yoh Sano1<\/sup> (1<\/sup>Department of Pharmacettical physicochemistry, Faculty of Pharmaceutical Sciences, Setsunan University, 2<\/sup>Department of Moecular Function and Physiology, Faculty of Pharmacy, Keio University. ) p.16<\/li>\n\n\n\n
    5. Age-related deamidations that lead to aggregation of crystallins in the lens \/ Kirsten. J. Lampi (Kirsten. J. Lampi) p.21<\/li>\n\n\n\n
    6. Folding and Amyloid Fibril Formation of Proteins \/ Y. Goto (Institute for Protein Research, Osaka Univ.) p.26<\/li>\n\n\n\n
    7. Elucidation of the trigger bringing a passive aggregation induced by tertiary or quaternary structural changes \/ Yukio MORIMOTO\uff08Research Reactor Institute, Kyoto University\uff09p.32<\/li>\n\n\n\n
    8. In situ Observation of Abnormal Aggregation by Small-Angle Neutron Scattering \/ Masaaki Sugiyama, Noriko Fujii, Yukio Morimoto, Toshiharu Fukunaga\uff08Research Reactor Institute, Kyoto University\uff09<\/li>\n\n\n\n
    9. Relationship between folding diseases and metabolic system of D-amino acid-containing protein \/ Tadatoshi Kinouchi and Noriko Fujii\uff08Research Reactor Institute, Kyoto University\uff09<\/li>\n\n\n\n
    10. The first target of radiation-induced carcinogenesis is protein, not DNA \/ Masami Watanabe\uff08Radiation Life Science, Research Reactor Institute, Kyoto University\uff09<\/li>\n<\/ol>\n\n\n\n

      <\/p>\n","protected":false},"excerpt":{"rendered":"

      \u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(I)\uff08\u5e73\u621020\u5e74\u5ea6\uff09Proceedings of the Specialist Research Meeting on “Abnormal […]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"12","format":"standard","meta":{"_uag_custom_page_level_css":"","_locale":"ja","_original_post":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/?p=2998","footnotes":""},"categories":[11],"tags":[],"class_list":["post-2998","post","type-post","status-publish","format-standard","hentry","category-kurri-report","ja"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"nakatani","author_link":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/author\/nakatani\/"},"uagb_comment_info":0,"uagb_excerpt":"\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(I)\uff08\u5e73\u621020\u5e74\u5ea6\uff09Proceedings…","_links":{"self":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/2998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/comments?post=2998"}],"version-history":[{"count":1,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/2998\/revisions"}],"predecessor-version":[{"id":2999,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/2998\/revisions\/2999"}],"wp:attachment":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/media?parent=2998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/categories?post=2998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/tags?post=2998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}