{"id":3052,"date":"2026-01-21T08:54:03","date_gmt":"2026-01-20T23:54:03","guid":{"rendered":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/?p=3052"},"modified":"2026-01-21T10:34:25","modified_gmt":"2026-01-21T01:34:25","slug":"kurri-kr-169","status":"publish","type":"post","link":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/kurri-kr-169\/","title":{"rendered":"KURRI-KR-169"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"86\" src=\"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-1024x86.png\" alt=\"\" class=\"wp-image-20\" srcset=\"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-1024x86.png 1024w, https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-300x25.png 300w, https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-768x64.png 768w, https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-1536x129.png 1536w, https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-content\/uploads\/sites\/6\/2025\/11\/KURNS_\u5efa\u7269\u30a4\u30e9\u30b9\u30c8_-1-2048x172.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"vk_block-margin-0--margin-bottom has-background has-heading-font-family has-small-font-size\" style=\"background-color:#e5e4e4\">\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(IV)\uff08\u5e73\u621023\u5e74\u5ea6\uff09<br>Proceedings of the Specialist Research Meeting on&#8221;Abnormal Protein Aggregation and the Folding Diseases, and Their Protection and Repair System&#8221;<\/p>\n\n\n\n<p class=\"vk_block-margin-0--margin-bottom vk_block-margin-0--margin-top has-background has-heading-font-family has-small-font-size\" style=\"background-color:#e5e4e4\">\u7de8\u96c6\uff1a\u5b9a\u91d1 \u8c4a\u3001\u85e4\u4e95\u7d00\u5b50<br>Edited by\uff1aYutaka Sadakane and Noriko Fujii<\/p>\n\n\n\n<p class=\"has-base-2-color has-text-color has-background has-link-color has-small-font-size wp-elements-b3d77a563bd5f25409467847f363fce7\" style=\"background-color:#0068b6;line-height:0.3\"><strong>\u76ee\u6b21<\/strong><\/p>\n\n\n\n<ol style=\"line-height:1.2\" class=\"wp-block-list has-small-font-size\">\n<li class=\"vk_block-margin-xxs--margin-bottom vk_block-margin-xxs--margin-top has-heading-font-family has-small-font-size\" style=\"line-height:1.2\">\u30b1\u30e9\u30c8\u30a8\u30d4\u30bb\u30ea\u30f3\u30da\u30d7\u30c1\u30c9\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u7dda\u7dad\u5f62\u6210\u306b\u5bfe\u3059\u308b\u8d85\u97f3\u6ce2\u3068\u754c\u9762\u6d3b\u6027\u5264\u306e\u52b9\u679c\/ \u516b\u6728\u5bff\u6893\u3001\u52a0\u85e4\u4f51\u5178\u3001\u5c0f\u6fa4\u5927\u4f5c \u3001\u52a0\u6cbb\u512a\u4e00 \u3001\u5f8c\u85e4\u7950\u5150\u3000 p.1<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u30d7\u30ea\u30aa\u30f3\u86cb\u767d\u8cea\u306e\u30b3\u30f3\u30db\u30e1\u30fc\u30b7\u30e7\u30f3\u30b9\u30a4\u30c3\u30c1 \/ \u6851\u7530\u4e00\u592b\u3000p.7<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u6297\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u7740\u76ee\u3057\u305f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u4e88\u9632\u306e\u53ef\u80fd\u6027 \/ \u6751\u4e0a\u4e00\u99ac\u3001\u5165\u6c5f\u4e00\u6d69\u3001\u6e05\u6c34\u5b5d\u5f66 p.10<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b3\u30f3\u30d5\u30a9\u30e1\u30fc\u30b7\u30e7\u30f3\u5909\u5316\u3068\u30a2\u30df\u30ed\u30a4\u30c9\u7dda\u7dad\u5f62\u6210\u306e\u5206\u5b50\u6a5f\u69cb \/ \u6cb3\u7530\u5eb7\u5fd7 p.15<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u86cb\u767d\u8cea\u4e2d\u306eAsp\u6b8b\u57fa\u306e\u7570\u6027\u5316\u304c\u86cb\u767d\u8cea\u7570\u5e38\u51dd\u96c6\u306e\u304d\u3063\u304b\u3051\u3067\u3042\u308b\/ \u85e4\u4e95\u7d00\u5b50 p.20<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u4e0d\u6eb6\u6027\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u53ef\u6eb6\u5316\u3068\u89e3\u6790 \/ \u4f50\u85e4\u3000\u7d00\u3001\u8c37\u53e3\u8cb4\u5b50\u3001\u5408\u7530\u6709\u4e00\u90ce\u3001\u5c0f\u5742\u6d69\u53f2\u3001\u6771\u91ce\u6052\u4f5c\u3001\u9152\u4e95\u7d00\u5178\u3001\u897f\u826f\u6d69\u4e00\u3001\u52a0\u85e4\u771f\u4ecb\u3001\u8c37\u53e3\u5bff\u7ae0\u3001\u5b89\u4e95\u590f\u751f p.25<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u76ae\u819a\u86cb\u767d\u8cea\u4e2d\u306eAsp\u6b8b\u57fa\u306eD\u4f53\u5316 \/ \u5b89\u5c90\u5065\u4e09\u3001\u68ee\u3000\u96c4\u5e73\u3001\u5c71\u4e2d\u5948\u6d25\u5b50\u3001\u85e4\u4e95\u667a\u5f66\u3001\u85e4\u4e95\u7d00\u5b50 p29<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u86cd\u5149\u76f8\u95a2\u5206\u5149\u6cd5\u3068\u8d85\u89e3\u50cf\u9855\u5fae\u93e1\u6cd5\u3092\u7528\u3044\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u51dd\u96c6\u904e\u7a0b\u306e\u7814\u7a76\/ \u5b88\u5c4b\u540d\u5948\u3001\u5317\u6751\u3000\u6717\u3001\u91d1\u57ce\u653f\u5b5d p.33<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u30bf\u30f3\u30d1\u30af\u8cea\u4e0d\u6eb6\u5316\u554f\u984c\u306b\u304a\u3051\u308b\u753b\u671f\u7684\u624b\u6cd5\u306e\u958b\u767a \/ \u516b\u8c37\u5982\u7f8e p.37<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u795e\u7d4c\u75be\u60a3\u306b\u95a2\u308f\u308b\u30da\u30d7\u30c1\u30c9\u65ad\u7247\u306e\u6a5f\u80fd\u3068\u30a2\u30df\u30ce\u9178\u30ec\u30d9\u30eb\u306e\u69cb\u9020\u5909\u5316\uff1a\u30a2\u30df\u30ed\u30a4\u30c9\u7e4a\u7dad\u5316\u3068\u7d30\u80de\u6bd2\u6027\u3078\u306e\u5f71\u97ff\u301c\u30a2\u30b9\u30d1\u30e9\u30ae\u30f3\u9178\u69cb\u9020\u5909\u5316\u306e\u901f\u5ea6\u8ad6\u306e\u691c\u8a0e \/ \u5b9a\u91d1\u3000\u8c4a p.42<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u30b3\u30f3\u30d5\u30a9\u30fc\u30e1\u30a4\u30b7\u30e7\u30f3\u75c5\u3068\u3057\u3066\u306e\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u3068\u30a2\u30b9\u30d1\u30e9\u30ae\u30f3\u9178\u6b8b\u57fa\u306e\u7570\u6027\u4f53\u5316\/ \u5c0f\u7b20\u539f\u6b63\u4eba p.47<\/li>\n\n\n\n<li class=\"has-heading-font-family\">MALDI -TOFMS\u306b\u3088\u308baA-\u30af\u30ea\u30b9\u30bf\u30ea\u30f3\u4e2d\u306eb-Asp\u6b8b\u57fa\u306e\u4e00\u6589\u89e3\u6790\/ \u85e4\u4e95\u667a\u5f66\u3001\u5c71\u5d0e\u96c4\u4e09\u3001\u85e4\u4e95\u7d00\u5b50 p.52 \u3000<\/li>\n\n\n\n<li class=\"has-heading-font-family\">\u74b0\u5883\u30b9\u30c8\u30ec\u30b9\u3068\u95a2\u9023\u3059\u308b\u8074\u899a\u7cfb\u75be\u60a3\u306e\u89e3\u6790\/ \u5927\u795e\u4fe1\u5b5d p.56<\/li>\n<\/ol>\n\n\n\n<p class=\"has-base-2-color has-text-color has-background has-link-color has-heading-font-family has-small-font-size wp-elements-c54793fe8f7401503ff451ac4d425941\" style=\"background-color:#0068b6;line-height:0.3\"><strong>Contents<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list vk_block-margin-0--margin-bottom vk_block-margin-xs--margin-top has-heading-font-family has-small-font-size\">\n<li class=\"vk_block-margin-xxs--margin-bottom vk_block-margin-xxs--margin-top has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Effects of ultrasonication and surfactant on amyloid fibril formation of keratoepithelin peptideson \/HisashiYagi, Yosuke Kato, Daisaku Ozawa, Yuichi Kaji and YujiGoto p.1<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Conformational switch of prion protein \/ Kazuo Kuwata p.7<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">The Prevention of Alzheimer\u2019s Disease Based on Anti-oxidative Stress\/ Kazuma Murakami, Kazuhiro Irie and Takahiko Shimizu p.10<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Molecular study on conformational changes and amyloid fibril formation of protein \/ Yasushi Kawata p.15<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Inversion of aspartyl residues may be one of triggers of abnormal aggregation of protein \/ Noriko Fujii p.20<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Solubilization and analysis of insoluble extracellular matrix \/ Nori Sato, Takako Taniguchi, Yuichiro Goda, Hirofumi Kosaka, Kosaku Higashino, Toshinori Sakai, Koichi Sairyo, Shinsuke Katoh, Hisaaki Tanighuchi, and Natsuo Yasui p.25<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Inversion of aspartyl residues in proteins from UV B-irradiated mouse skin \/ Kenzo Aki, Yuhei Mori, Natsuko Yamanaka, Norihiko Fujii, Noriko Fujii p.29<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Protein aggregation studied in living cell by fluorescence correlation spectroscopy and super resolution microscopy \/ Moriya Nana, Akira Kitamura and Masataka Kinjo p.33<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Application of new scientific discovery to the detection and destruction of protein aggregates\/ Naomi Hachiya\u3000p.37<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Effect of structural alteration and deletion of specific amino acid in the peptide fragments related to neuronal diseases on amyloid fiber formation and cytotoxicity \/ Yutaka Sadakane\u3000p.42<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Idiopathic lung fibrosis as a conformational disease and isomerization of Asp residues\/Masahito Ogasawara p.47<\/li>\n\n\n\n<li class=\"has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Identification of \u00ae-aspartyl residues in aA-crystallin by MALDI-TOFMS \/ Norihiko Fujii, Yuzo Yamazaki and Noriko Fujii p.52<\/li>\n\n\n\n<li class=\"vk_block-margin-xxs--margin-bottom vk_block-margin-xxs--margin-top has-heading-font-family has-small-font-size\" style=\"line-height:1.4\">Analysis of environmental stress-related hearing impairment \/ Nobutaka Ohgami p.56<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(IV)\uff08\u5e73\u621023\u5e74\u5ea6\uff09Proceedings of the Specialist Research Meeting on&#8221;Abnormal  [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"12","format":"standard","meta":{"_uag_custom_page_level_css":"","_locale":"ja","_original_post":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/?p=3052","footnotes":""},"categories":[11],"tags":[],"class_list":["post-3052","post","type-post","status-publish","format-standard","hentry","category-kurri-report","ja"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"nakatani","author_link":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/author\/nakatani\/"},"uagb_comment_info":0,"uagb_excerpt":"\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u51dd\u96c6\u3068\u305d\u306e\u9632\u5fa1\u30fb\u4fee\u5fa9\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u7814\u7a76\u5c02\u9580\u7814\u7a76\u4f1a\u5831\u544a(IV)\uff08\u5e73\u621023\u5e74\u5ea6\uff09Proceeding&hellip;","_links":{"self":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/3052","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/comments?post=3052"}],"version-history":[{"count":2,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/3052\/revisions"}],"predecessor-version":[{"id":3088,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/3052\/revisions\/3088"}],"wp:attachment":[{"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/media?parent=3052"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/categories?post=3052"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/wp-json\/wp\/v2\/tags?post=3052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}