{"id":4359,"date":"2026-05-14T14:05:23","date_gmt":"2026-05-14T05:05:23","guid":{"rendered":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/?p=4359"},"modified":"2026-05-14T14:06:46","modified_gmt":"2026-05-14T05:06:46","slug":"kurri-tr-260","status":"publish","type":"post","link":"https:\/\/adm.rri.kyoto-u.ac.jp\/pub\/kurri-tr-260\/","title":{"rendered":"KURRI-TR-260"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u60aa\u6027\u9ed2\u8272\u816b\u306e\u4ee3\u8b1d\u6d3b\u6027\u306b\u3088\u308b\u539f\u5b50\u7089\u6cbb\u7642\u306e\u5c55\u958b\u306b\u95a2\u3059\u308b\u7814\u7a76
Selective Thermal Neutron Capture Treatment of Malignant Melanoma Using its Specific Metabolic Activity<\/p>\n\n\n\n

1985\u5e741\u6708\u3000(January, 1985)
\u7de8\u96c6\uff1a\u4e09\u5cf6\u8c4a
Edited by\uff1a Yutaka Mishima<\/p>\n\n\n\n

\u76ee\u6b21<\/strong> <\/p>\n\n\n\n

\u307e\u3048\u304c\u304d \/\u00a0 \u7814\u7a76\u4ee3\u8868\u8005 \u795e\u6238\u5927\u5b66\u533b\u5b66\u90e8 \u6559\u6388 \u4e09\u5cf6\u8c4a\u00a0 \/p.\u216a<\/p>\n\n\n\n

    \n
  1. Cure of Malignant Melanoma by Single Thermal Neutron Capture Treatment Using Melanoma-Seeking Compounds : 10<\/sup>B\/Melanogenesis Interaction to In Vitro\/In Vivo Radiobiological Analysis to Preclinical Studies \/ Yutaka Mishima, Masamitsu Ichihashi, Takafumi Nakanishi, Masayuki Tsuji, Masato Ueda, Susumu Hatta, Toshio Nakagawa (Department of Dermatology, Kobe University School of Medicine), Tatsuo Suzuki, Tsunenori Suganuma and Kohsaku Kobayashi (School of Veterinary Medicine, Azabu University)\u00a0 \/p.1<\/li>\n\n\n\n
  2. \u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u306b\u304a\u3051\u308b\u9ed2\u8272\u816b\u62c5\u764c\u30cf\u30e0\u30b9\u30af\u30fc\u306e\u8ee2\u79fb\u89e3\u6790 \/\u00a0 \u4e0a\u7530\u6b63\u767b\uff0c \u4e09\u5cf6\u8c4a\uff0c \u5e02\u6a4b\u6b63\u5149\uff08 \u795e\u6238\u5927\u533b\uff09\u00a0 \/p.15<\/li>\n\n\n\n
  3. In Vitro Radio biological Evaluation of Selective Killing Effects of 10<\/sup>B1<\/sub> -para-boronophenylalanine\u30fbHCl in the Thermal Neutron Capture Therapy of Malignant Melanoma Cells \/ Masamitsu Ichihashi, Masato Ueda, Kazuhito Hayashibe, Susumu Hatta, Masayuki Tsuji, Yu taka Mishima (Department of Dermatology, Kobe University School of Medicine), Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University), Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.23<\/li>\n\n\n\n
  4. 4Specific Killing Effect of 10<\/sup>B1<\/sub>Para-boronophenylalaninein Thermal Neutron Capture Therapy of Malignant Melanoma : In Vitro Radiobiological Evaluation \/ Masamitsu Ichihashi, Takafumi Nakanishi and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.33<\/li>\n\n\n\n
  5. 10<\/sub>B1<\/sub> -paraboronophenylalanine\u30fbHCl\u306e\u9078\u629e\u7684\u9ed2\u8272\u816b\u89aa\u548c\u6027\uff1a\u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u306e\u305f\u3081\u306b \/ \u8fbb\u6b63\u5e78\u3001\u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.37<\/li>\n\n\n\n
  6. Thermal Neutron Capture Therapy of Malignant Melanoma : in vitro Radiobiological Analysis \/ Takafumi Nakanishi, Masamitsu Ichihashi, Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine), Taiju Matsuzawa and Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University)\u00a0 \/p.43<\/li>\n\n\n\n
  7. 10<\/sub>B1<\/sub>-paraboronophenylalanine\u306e\u751f\u4f53\u5185\u52d5\u614b\u30a2\u30df\u30ce\u9178\u81ea\u52d5\u5206\u6790\u53ca\u3073\u8584\u5c64\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30d5\u30a3\u30fc\u6cd5 \/ \u85e4\u539f\u5bdb\uff0c \u85e4\u4e95\u82b3\u592b\uff0c \u52a0\u85e4\u7d00\u5b50\uff0c \u8fbb\u6b63\u5e78, \u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\u3001\u7530\u4e2d\u5343\u8cc0\u5b50\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.51<\/li>\n\n\n\n
  8. 10<\/sub>B1<\/sub>-paraboronophenylalanine\u306e\u5fae\u91cf\u5b9a\u91cf \/ \u85e4\u539f\u5bdb\u3001\u85e4\u4e95\u82b3\u592b\u3001\u7530\u4e2d\u5343\u8cc0\u5b50\u3001\u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.55<\/li>\n\n\n\n
  9. \u9ed2\u8272\u816b\u62c5\u764c\u30cf\u30e0\u30b9\u30af\u30fc\u306e\u9078\u629e\u7684\u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u30fc\u96fb\u5b50\u7dda\u7167\u5c04\u3068\u306e\u6bd4\u8f03\u89e3\u6790 \/ \u5e73\u585a\u7d14\u4e00\u3001\u6728\u6751\u4fee\u6cbb\uff08\u795e\u6238\u5927\u533b\uff09\u8f9b\u5d8b\u535a\uff08\u5175\u5eab\u6210\u4eba\u75c5\u30bb\u30f3\u30bf\u30fc\uff09\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.59<\/li>\n\n\n\n
  10. \u539f\u5b50\u7089\u306b\u3088\u308b\u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u306e\u81e8\u5e8a\u306b\u5411\u3051\u3066\u306e\u4eba\u9aa8\u5165\u308a\u4eba\u4f53Phantom\u7167\u5c04\u5b9f\u9a13\u306b\u65bc\u3051\u308b\u7dda\u91cf\u6e2c\u5b9a \/ \u8f9b\u5d8b\u535a\uff08\u5175\u5eab\u6210\u4eba\u75c5\u30bb\u30f3\u30bf\u30fc\uff09\u5e73\u585a\u7d14\u4e00\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.63<\/li>\n\n\n\n
  11. \u03b1-\u30c8\u30e9\u30c3\u30af\u6cd5\u306b\u3088\u308bBoron-10\u306e\u4f53\u5185\u5206\u5e03\u6e2c\u5b9a \/ \u9ad8\u57a3\u653f\u96c4\uff08\u5c71\u5f62\u5927\u533b\uff09\u3001\u4e09\u5cf6\u8c4a\uff0c \u5e02\u6a4b\u6b63\u5149\uff08\u795e\u6238\u5927\u533b\uff09\u798f\u7530\u5bdb\u3001\u677e\u6ca2\u5927\u6a39\uff08\u6771\u5317\u5927\uff09\u00a0 \/p.69<\/li>\n\n\n\n
  12. Boronic, Diboronic and a-Amino.-boronic Acids Derived from l-Ethynyl-3, 4 dimethoxybenzene \/ Toshia Nakagawa and Yu taka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.73<\/li>\n\n\n\n
  13. \u60aa\u6027\u9ed2\u8272\u816b\u306e\u901f\u4e2d\u6027\u5b50\u7dda\u6cbb\u7642\u81e8\u5e8a\u30c8\u30e9\u30a4\u30a2\u30eb \/ \u6052\u5143\u535a\u3001\u68ee\u7530\u65b0\u516d\u3001\u77f3\u5ddd\u9054\u96c4\uff08\u653e\u5c04\u7dda\u533b\u7814\uff09\u00a0 \/p.83<\/li>\n\n\n\n
  14. \u30cc\u30fc\u30c9\u30de\u30a6\u30b9\u53ef\u79fb\u690d\u30d2\u30c8\u9ed2\u8272\u816b\u682a\u306b\u3088\u308b\u9078\u629e\u7684\u71b1\u4e2d\u6027\u5b50\u6355\u6349\u6cbb\u7642\u30e2\u30c7\u30eb\u306e\u691c\u8a0e \/ \u7389\u5185\u79c0\u4e00\u3001\u7389\u7f6e\u61b2\u4e00\uff08\u6771\u6d77\u5927\u533b\uff09\u4e0a\u7530\u6b63\u767b\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.91<\/li>\n\n\n\n
  15. Shared Antigenic Determinant Expressed on Various Mammalian Melanoma Cells \/ Masaru Taniguchi (Department of Immunology, Chiba University School of Medicine) and Seiji Wakabayashi (Department of Dermatology, Chiba University School of Medicine)\u00a0 \/p.95<\/li>\n\n\n\n
  16. Sandwich Radioimmunoassay Using Single Monoclonal Antibody That Detects Minute Amounts of Melanoma Antigens from Various Mammalian Species \/ Seiji Wakabayashi, Shoji Okamoto (Department of Dermatology, Chiba University School of Medicine) and Masaru Taniguchi (Department of Immunology, Chiba University School of Medicine)\u00a0 \/p.105<\/li>\n\n\n\n
  17. \u751f\u4f53\u30d5\u30a1\u30f3\u30c8\u30e0\u5185\u306e\u71b1\u4e2d\u6027\u5b50\u5206\u5e03 \/ \u67f4\u7530\u4fca\u4e00\u3001\u4f50\u85e4\u5b5d\u53f8\u3001\u5c0f\u91ce\u5149\u30fc\uff08\u4eac\u5927\u539f\u5b50\u7089\uff09\u00a0 \/p.111<\/li>\n\n\n\n
  18. \u4e2d\u6027\u5b50\u6355\u7372\u7642\u6cd5\u306b\u304a\u3051\u308b\u7269\u7406\u5de5\u5b66\u9762\u306e\u9032\u6b69 \u751f\u4f53\u4e2d\u306eppm\u30aa\u30fc\u30c010<\/sup>B\u6fc3\u5ea6\u306e\u6e2c\u5b9a\u6cd5\u306e\u958b\u767a\u3068\u91cd\u6c34\u306e(\u03b3, n)\u53cd\u5fdc\u306e\u4e2d\u6027\u5b50\u5834\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306e \u8a55\u4fa1 \/ \u795e\u7530\u5553\u6cbb\u3001\u53e4\u6797\u5fb9\u3001\u9752\u6728\u4e00\u5f66\uff08\u4eac\u5927\u539f\u5b50\u7089\uff09\u00a0 \/p.117<\/li>\n\n\n\n
  19. \u4e2d\u6027\u5b50\u6355\u7372\u7642\u6cd5\u306b\u304a\u3051\u308b\u9078\u629e\u7684\u7167\u5c04\u6280\u8853\u304a\u3088\u3073\u7167\u5c04\u7dda\u91cf\u8a55\u4fa1\u306e\u539f\u5b50\u7089\u7269\u7406\u5de5\u5b66\u7684\u691c\u8a0e\/ \u53e4\u6797\u5fb9\u3001\u795e\u7530\u5553\u6cbb\uff08\u4eac\u5927\u539f\u5b50\u7089\uff09\u00a0 \/p.133<\/li>\n\n\n\n
  20. Analytical Calculation of Boron-10 Dosage in Cell Nucleus for Neutron Capture Therapy \/Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.145<\/li>\n\n\n\n
  21. Microanalysis System of ppm-order 10<\/sup>B Concentrations in Tissue for Neutron Capture Therapy by Prompt Gamma-ray Spectrometry \/ Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.163<\/li>\n\n\n\n
  22. Phantom Experiment and Analysis for in vivo Measurement of Boron-10 Concentrations in Melanoma for Boron Neutron Capture Therapy \/ Kazuhiko Aoki, Tooru Kobayashi, and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.171<\/li>\n\n\n\n
  23. \u9ed2\u8272\u816b\u306e\u9078\u629e\u7684\u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u306b\u304a\u3051\u308b\u7d30\u80de\u81f4\u6b7b\u52b9\u679c\u306e\u751f\u7269\u5b66\u7684\u7814\u7a76 \/ \u6c5f\u53e3\u543e\u6717\u3001\u5150\u7389\u9686\u6cbb\u3001\u963f\u5f62\u6e05\u548c\u3001\u9ed2\u5ca9\u5e38\u7965\uff08\u5ca1\u5d0e\u57fa\u790e\u751f\u7814\uff09\u5ca1\u672c\u5149\u6b63\uff08\u540d\u5927\u7406\uff09\u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.181<\/li>\n\n\n\n
  24. Regeneration of the Lens as a Phenomenon of Cellular Transdifferentiation : Regulability of the Differentiated State of the Vertebrate Pigment Epithelial Cell \/ Goro Eguchi (Institute of Molecular Biology, Faculty of Science, Nagoya University) and Yoshiaki ltoh (Laboratory for Biology, Aichi Medical University)\u00a0 \/p.191<\/li>\n\n\n\n
  25. \u71b1\u4e2d\u6027\u5b50\u6355\u6349\u53cd\u5fdc\u306eRBE\u306e\u8a55\u4fa1\u306b\u3064\u3044\u3066\u4e00\u6570\u5f0f\u8a08\u7b97\u30e2\u30c7\u30eb\u306b\u3088\u308b\u8a55\u4fa1\uff0d \/ \u798f\u7530\u5bdb\uff08\u6771\u5317\u5927\uff09\u53e4\u6797\u5fb9\u3001\u795e\u7530\u5553\u6cbb\uff08\u4eac\u5927\u539f\u5b50\u7089\uff09\u677e\u6fa4\u5927\u6a39\uff08\u6771\u5317\u5927\uff09\u00a0 \/p.197<\/li>\n\n\n\n
  26. \u57f9\u990a\u7d30\u80de\u306e\u71b1\u4e2d\u6027\u5b50\u7167\u5c04\u5b9f\u9a13\u306b\u304a\u3051\u308b\u4e2d\u6027\u5b50\u30d5\u30eb\u30a8\u30f3\u30b9\u306e\u6e2c\u5b9a\u306b\u3064\u3044\u3066 \/ \u798f\u7530\u5bdb\uff08\u6771\u5317\u5927\uff09\u53e4\u6797\u5fb9\uff08\u4eac\u5927\u539f\u5b50\u7089\uff09\u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u677e\u6fa4\u5927\u6a39\uff08\u6771\u5317\u5927\uff09\u00a0 \/p.203<\/li>\n\n\n\n
  27. \u71b1\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5\u306b\u304a\u3051\u308b\u969c\u5bb3\u4fee\u5fa9\u6a5f\u69cb\u306e\u89e3\u6790\/ \u5185\u6d77\u535a\u53f8\uff08\u4eac\u5927\u533b\uff09\u5e02\u6a4b\u6b63\u5149\u3001\u4e09\u5cf6\u8c4a\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.209<\/li>\n\n\n\n
  28. Enhancement of Thermal Neutron-Induced Killing Effect on HeLa Cells by Means of Three 10-Boron-Compounds \/ Yowri Jeno (Department of Experimental Radiology, Faculty of Medicine, Kyoto University)\u00a0 \/p.219<\/li>\n\n\n\n
  29. 11<\/sup>B, 13<\/sup>C-NMR Study of the Complex Formation of Phenylboronate with Catechol and L-Dopa \/ Kazuo Yoshino, Satoshi Oguchi, Yuji Shimakata, Yoshihiro Mori (Department of Chemistry, Shinshu University), Makoto Okamoto, Masahiro Kotaka (Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology) and Hidetake Kakihana (Department of Chemistry, Sophia University)\u00a0 \/p.221<\/li>\n\n\n\n
  30. \u751f\u4f53\u7d44\u7e54\u4e2d\u306e\u5fae\u91cf\u30db\u30a6\u7d20\u306e\u5316\u5b66\u5206\u6790\u306b\u3088\u308b\uff0cMelanoma-seeking agent, 10<\/sup>B1<\/sub>-p-Borono- phenylalanine\u30fbHCI\u306e\u7814\u7a76 \/\u5409\u91ce\u548c\u592b\uff08 \u4fe1\u5dde\u5927\u7406\uff09\u5ca1\u672c\u771f\u5b9f\uff08\u6771\u5de5\u5927\u539f\u5b50\u7089\uff09\u57a3\u82b1\u79c0\u6b66\uff08\u4e0a\u667a\u5927\u7406\uff09\u68ee\u82b3\u5f18\uff08\u4fe1\u5dde\u5927\u7406\uff09\u4e09\u5cf6\u8c4a\u3001\u5e02\u6a4b\u6b63\u5149\u3001\u8fbb\u6b63\u5e78\u3001\u4e2d\u897f\u5b5d\u6587\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.233<\/li>\n\n\n\n
  31. Spectrophotometric Determination of Trace Boron in Biological Materials after Alkali Fusion Decomposition \/Kazuo Yoshino, Makoto Okamoto, and Hidetake Kakihana (Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology) Takafumi Nakanishi, Masamitsu Ichihashi, and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.247<\/li>\n\n\n\n
  32. 10<\/sup>B1<\/sub> -paraboronophenylalanine\u30fbHCl\u306e\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u6025\u6027\u6bd2\u6027 \/ \u8c37\u5c71\u7d18\u592a\u90ce\u3001\u85e4\u539f\u5bdb\u3001\u7530\u4e2d\u5343\u8cc0\u5b50\uff08\u795e\u6238\u5927\u533b\uff09\u00a0 \/p.251<\/li>\n<\/ol>\n\n\n\n

    Conents<\/strong><\/p>\n\n\n\n

    Preface \/\u00a0 Preface Yut aka Mishima (Department of Dermatology, Kobe University School of Medicine\u00a0 \/p.\u216a<\/p>\n\n\n\n

      \n
    1. Cure of Malignant Melanoma by Single Thermal Neutron Capture Treatment Using Melanoma-Seeking Compounds : 10<\/sup>B\/Melanogenesis Interaction to In Vitro\/In Vivo Radiobiological Analysis to Preclinical Studies \/ Yutaka Mishima, Masamitsu Ichihashi, Takafumi Nakanishi, Masayuki Tsuji, Masato Ueda, Susumu Hatta, Toshio Nakagawa (Department of Dermatology, Kobe University School of Medicine), Tatsuo Suzuki, Tsunenori Suganuma and Kohsaku Kobayashi (School of Veterinary Medicine, Azabu University)\u00a0 \/p.1<\/li>\n\n\n\n
    2. Effects of Thermal Neutron Capture Therapy on Melanoma Metastasis \/\u00a0 Masato Ueda, Yutaka Mishima and Masamitsu Ichihashi (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.15<\/li>\n\n\n\n
    3. In Vitro Radio biological Evaluation of Selective Killing Effects of 10<\/sup>B1<\/sub> -para-boronophenylalanine\u30fbHCl in the Thermal Neutron Capture Therapy of Malignant Melanoma Cells \/ Masamitsu Ichihashi, Masato Ueda, Kazuhito Hayashibe, Susumu Hatta, Masayuki Tsuji, Yu taka Mishima (Department of Dermatology, Kobe University School of Medicine), Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University), Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.23<\/li>\n\n\n\n
    4. Specific Killing Effect of 10<\/sup>B1<\/sub>Para-boronophenylalaninein Thermal Neutron Capture Therapy of Malignant Melanoma : In Vitro Radiobiological Evaluation \/ Masamitsu Ichihashi, Takafumi Nakanishi and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.33<\/li>\n\n\n\n
    5. Selective Affinity of 10<\/sup>B1<\/sub>– paraboronophenylalanine\u30fbHCIto Malignant Melanoma; In Relation to Thermal Neutron Capture Therapy \/ Masayuki Tsuji, Masamitsu Ichihashi and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.37<\/li>\n\n\n\n
    6. Thermal Neutron Capture Therapy of Malignant Melanoma : in vitro Radiobiological Analysis \/ Takafumi Nakanishi, Masamitsu Ichihashi, Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine), Taiju Matsuzawa and Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University)\u00a0 \/p.43<\/li>\n\n\n\n
    7. Dynamics of10<\/sup>B1<\/sub> paraboronophenylalanine Accumulation, Metabolism and Excretion : Amino Acid Auto analytical and Thin Layer Chromatographic Studies \/ Hiroshi Fujiwara, Yoshio Fujii, Noriko Katoh, Chikako Tanaka (Department of Pharmacology, Kobe University School of Medicine), Masayuki Tsuji, Masamitsu Ichihashi and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine\u00a0 \/p.51<\/li>\n\n\n\n
    8. \u00a0<\/sub>Microdetermination of 10<\/sup>B1 <\/sub>paraboronophenylalanine \/ Hiroshi Fujiwara, Yoshio Fujii, Chikako Tanaka (Department of Pharmacology, Kobe University School of Medicine), Masamitsu Ichihashi and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.55<\/li>\n\n\n\n
    9. RBE(Relative Biological Effectiveness) of Thermal Neutron Capture Therapy of Malignant Melanoma Compared with 9MeV Electron Beam Irradiation \/ Junichi Hiratsuka, Shuji Kimura (Department of Radiology, Kobe University School of Medicine), Hiroshi Karashima (Hyogo Medical Center for Adults) and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.59<\/li>\n\n\n\n
    10. Clinical Dosimetry Using Human Phantom with Skeletal Bone for Thermal Neutron Capture Therapy \/ Hiroshi Karashima (Hyogo Medical Center for Adults), Junichi Hiratsuka (Department of Radiology, Kobe University School of Medicine) and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.63<\/li>\n\n\n\n
    11. Imaging of Boron-IO Distribution in Tissue and It’s Quantitative Analysis Using a-track Autoradiography \/\u00a0 Masao Takagaki (Yamagata University School of Medicine), Yutaka Mishima, Masamitsu Ichihashi (Department of Dermatology, Kobe University School of Medicine), Hiroshi Fukuda and Taiju Matsuzawa (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University)\u00a0 \/p.69<\/li>\n\n\n\n
    12. Boronic, Diboronic and a-Amino.-boronic Acids Derived from l-Ethynyl-3, 4 dimethoxybenzene \/ Toshia Nakagawa and Yu taka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.73<\/li>\n\n\n\n
    13. Clinical Trial with Fast Neutrons for malignant Melanoma \/ Hiroshi Tsunemoto, Shinroku Morita and Tatsuo Ishikawa (National Institute of Radiological Sciences)\u00a0 \/p.83<\/li>\n\n\n\n
    14. Therapeutic Model in Nude Mice Carrying Transplanted Human Melanoma Line: Studies of Selective Thermal Neutron Capture Therapy \/ Hidekazu Tamauchi, Norikazu Tamaoki (Department of Pathology, Tokai University School of Medicine), Masato Ueda and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.91<\/li>\n\n\n\n
    15. Shared Antigenic Determinant Expressed on Various Mammalian Melanoma Cells \/ Masaru Taniguchi (Department of Immunology, Chiba University School of Medicine) and Seiji Wakabayashi (Department of Dermatology, Chiba University School of Medicine)\u00a0 \/p.95<\/li>\n\n\n\n
    16. Sandwich Radioimmunoassay Using Single Monoclonal Antibody That Detects Minute Amounts of Melanoma Antigens from Various Mammalian Species \/ Seiji Wakabayashi, Shoji Okamoto (Department of Dermatology, Chiba University School of Medicine) and Masaru Taniguchi (Department of Immunology, Chiba University School of Medicine)\u00a0 \/p.105<\/li>\n\n\n\n
    17. Thermal Neutron Flux Distribution in Phan tom \/ Toshikazu Shibata, Takashi Sato and Koichi Ono (Research Reactor Institute, Kyoto University\u00a0 \/p.111<\/li>\n\n\n\n
    18. Progress of Physics and Technology for Neutron Capture Therapy-Development of Measurement of ppm-order 10<\/sup>B Concentrationin vivo <\/em>and Estimation of Effect of (\u03b3, n) Reaction of Heavy Water on Neutron Field \/ Keiji Kanda, Tooru Kobayashi and Kazuhiko Aoki (Research Reactor Institute, Kyoto University)\u00a0 \/p.117<\/li>\n\n\n\n
    19. Selective Irradiation Technique and Dose Estimation for Neutron Capture Therapy\/ Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.133<\/li>\n\n\n\n
    20. Analytical Calculation of Boron-10 Dosage in Cell Nucleus for Neutron Capture Therapy \/Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.145<\/li>\n\n\n\n
    21. Microanalysis System of ppm-order 10<\/sup>B Concentrations in Tissue for Neutron Capture Therapy by Prompt Gamma-ray Spectrometry \/ Tooru Kobayashi and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.163<\/li>\n\n\n\n
    22. Phantom Experiment and Analysis for in vivo Measurement of Boron-10 Concentrations in Melanoma for Boron Neutron Capture Therapy \/ Kazuhiko Aoki, Tooru Kobayashi, and Keiji Kanda (Research Reactor Institute, Kyoto University)\u00a0 \/p.171<\/li>\n\n\n\n
    23. Biological Approach to the Killing Effect of Thermal Neutron Capture Therapy on Cultured B-16 Melanoma Cells \/ Goro Eguchi, Ryuji Kodama, Kiyokazu Agata, Tsuneyoshi Kuroiwa (The National Institute for Basic Biology, Department of Developmental Biology), Mitsumasa Okamoto (Institute of Molecular Biology, Faculty of Science, Nagoya University), Masamitsu Ichihashi and Yutaka Mishima (Department of Dermatology, Kobe University school of Medicine)\u00a0 \/p.181<\/li>\n\n\n\n
    24. Regeneration of the Lens as a Phenomenon of Cellular Transdifferentiation : Regulability of the Differentiated State of the Vertebrate Pigment Epithelial Cell \/ Goro Eguchi (Institute of Molecular Biology, Faculty of Science, Nagoya University) and Yoshiaki ltoh (Laboratory for Biology, Aichi Medical University)\u00a0 \/p.191<\/li>\n\n\n\n
    25. RBEs of Thermal Neutron Capture Therapy: Estimation by Theoretical Calculation \/ Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University), Tooru Kobayashi, Keiji Kanda (Research Reactor Institute, Kyoto University) and Taiju Matsuzawa (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University)\u00a0 \/p.197<\/li>\n\n\n\n
    26. Estimation of Fluence of Thermal Neutron Capture Therapy Using Cultured Melanoma Cell \/ Hiroshi Fukuda (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University), Tooru Kobayashi (Research Reactor Institute, Kyoto University), Masamitsu Ichihashi (Department of Dermatology, Kobe University School of Medicine) and Taiju Matsuzawa (Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and Cancer, Tohoku University)\u00a0 \/p.203<\/li>\n\n\n\n
    27. Cellular Damage and Repair in Thermal Neutron Cap-ture Therapy of Malignant Melanoma\/ Hiroshi Utsumi(Radiation Biology Center, Kyoto University), Masamitsu Ichihashi and Yu taka Mishima (Department of Derma to logy, Kobe University School of Medicine)\u00a0 \/p.209<\/li>\n\n\n\n
    28. Enhancement of Thermal Neutron-Induced Killing Effect on HeLa Cells by Means of Three 10-Boron-Compounds \/ Yowri Jeno (Department of Experimental Radiology, Faculty of Medicine, Kyoto University)\u00a0 \/p.219<\/li>\n\n\n\n
    29. 11<\/sup>B, 13<\/sup>C-NMR Study of the Complex Formation of Phenylboronate with Catechol and L-Dopa \/ Kazuo Yoshino, Satoshi Oguchi, Yuji Shimakata, Yoshihiro Mori (Department of Chemistry, Shinshu University), Makoto Okamoto, Masahiro Kotaka (Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology) and Hidetake Kakihana (Department of Chemistry, Sophia University)\u00a0 \/p.221<\/li>\n\n\n\n
    30. Study of Melanoma Seeking Agent, 10<\/sup>B1<\/sub>-p-Boronophenylalanine\u30fbHCIby Chemical Determination of Trace Boron in Biological Materials \/ Kazuo Yoshino (Department of Chemistry, Shinshu University), Makoto Okamoto (Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology), Hide take Kakihana (Department of Chemistry, Sophia University), Yoshihiro Mori (Department of Chemistry, Shinshu University), Yutaka Mishima, Masamitsu lchihashi, Masayuki Tsuji and Takafumi Nakanishi (Department of Dermatology, Kobe University School of Medicine)\uff09\u00a0 \/p.233<\/li>\n\n\n\n
    31. Spectrophotometric Determination of Trace Boron in Biological Materials after Alkali Fusion Decomposition \/Kazuo Yoshino, Makoto Okamoto, and Hidetake Kakihana (Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology) Takafumi Nakanishi, Masamitsu Ichihashi, and Yutaka Mishima (Department of Dermatology, Kobe University School of Medicine)\u00a0 \/p.247<\/li>\n\n\n\n
    32. Acute Toxicity of 110<\/sup>B1<\/sub>-Paraboronophenylalanine\u30fbHCIin Mice \/ Koh taro Taniyama, Hiroshi Fujiwara and Chikako Tanaka (Department of Pharmacology, Kobe University School of Medicine)\u00a0 \/p.251<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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